What Can Chemical Carcinogenesis Shed Light on the LNT Hypothesis in Radiation Carcinogenesis?
نویسندگان
چکیده
منابع مشابه
Chemical carcinogenesis.
The use of chemical compounds benefits society in a number of ways. Pesticides, for instance, enable foodstuffs to be produced in sufficient quantities to satisfy the needs of millions of people, a condition that has led to an increase in levels of life expectancy. Yet, at times, these benefits are offset by certain disadvantages, notably the toxic side effects of the chemical compounds used. E...
متن کاملThresholds in chemical carcinogenesis.
It is common practice to base carcinogenic risk assessment on the view that there is no threshold for chemical carcinogenesis. In this context, the threshold is defined as a dose below which no effects are observed. Analysis of epidemiological and experimental data on chemical carcinogenesis confirms that no thresholds have been demonstrated in human or animal studies, including the ED01 study ...
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Objective(s):Green tea (GT) is one of the most popular beverages worldwide whose beneficial effects on health have been demonstrated. Recent studies suggest that GT may contribute to reduction of cancer risk and progression. The aim of this study was to evaluate the effects of whole GT on urinary bladder chemical carcinogenesis in male and female ICR mice. Materials and Methods: The GT charact...
متن کاملOncogenes and radiation carcinogenesis.
Current research indicates a role for several oncogenes in radiation-induced carcinogenesis in vivo and cell transformation in vitro. Certain oncogenes are probably also involved in some cases of human cancer caused by exposure to nonionizing radiation and may play a mechanistic role in the phenomenon of radioresistance seen in later stages of tumor progression. The mechanisms of oncogene activ...
متن کاملRisk of Radiation Carcinogenesis
Occupational radiation exposure from the space environment may increase cancer morbidity or mortality risk in astronauts. This risk may be influenced by other space fl ight factors including microgravity and e nvironmental contaminants. A Mars mission will not be fe asible unless improved shielding is developed or transit time is decreased. – Human Research Program Requirements Document, HRP-47...
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ژورنال
عنوان ژورنال: Dose-Response
سال: 2019
ISSN: 1559-3258,1559-3258
DOI: 10.1177/1559325819876799